RNA Details
Disease Name
heart failure
Tissue
heart
RNA Symbol
mir-377
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
PCR
Target
NA
Pathway
NA
PubMed ID
Title
Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377
Year
2015
Function
"Heart failure(HF) increased miR-377 expression in the myocardium, which is detrimental to stem cell function, and transplantation of miR-377 knockdown HCD34(+) cells into ischemic myocardium promoted their angiogenic ability, attenuating left ventricular remodeling and cardiac fibrosis."